Recent literature hints that outcomes of clinical trials in medicine are selectively reported. If applicable to psychotic disorders, such bias would jeopardize the reliability of randomized clinical trials (RCTs) investigating antipsychotics and thus their extrapolation to clinical practice. We therefore comprehensively examined outcome reporting bias in RCTs of antipsychotic drugs by a systematic review of prespecified outcomes on ClinicalTrials.gov records of RCTs investigating antipsychotic drugs in schizophrenia and schizoaffective disorder between 1 January 2006 and 31 December 2013. These outcomes were compared with outcomes published in scientific journals. Our primary outcome measure was concordance between prespecified and published outcomes; secondary outcome measures included outcome modifications on ClinicalTrials.gov after trial inception and the effects of funding source and directionality of results on record adherence. Of the 48 RCTs, 85% did not fully adhere to the prespecified outcomes. Discrepancies between prespecified and published outcomes were found in 23% of RCTs for primary outcomes, whereas 81% of RCTs had at least one secondary outcome non-reported, newly introduced, or changed to a primary outcome in the respective publication. In total, 14% of primary and 44% of secondary prespecified outcomes were modified after trial initiation. Neither funding source (P=0.60) nor directionality of the RCT results (P=0.10) impacted ClinicalTrials.gov record adherence. Finally, the number of published safety endpoints (N=335) exceeded the number of prespecified safety outcomes by 5.5 fold. We conclude that RCTs investigating antipsychotic drugs suffer from substantial outcome reporting bias and offer suggestions to both monitor and limit such bias in the future.

The goal of this project is to provide high-quality, accessible primary sources to those teaching and studying the histories and cultures of the Spanish-speaking world and the indigenous peoples of Latin America. Our modules cover a wide range of topics, but all consist of the same essential parts:

This collection uses primary sources to explore the construction of the Panama Canal. Digital Public Library of America Primary Source Sets are designed to help students develop their critical thinking skills and draw diverse material from libraries, archives, and museums across the United States. Each set includes an overview, ten to fifteen primary sources, links to related resources, and a teaching guide. These sets were created and reviewed by the teachers on the DPLA's Education Advisory Committee.

Pandora, CO Mining Town. Western Mining History presents a brief summary of Colorado's Historical Mining Towns with links to additional Colorado resources for a mining town database and mines by county. Western Mining History is an historical site that provides information on mining, mining towns, the gold and silver rush, and Photos and maps of the western United States. This is a strong primary source resource that can be used for a variety of class research projects. Consider becoming a member or making a donation to help further the work of the site.

This Western Mining History database uses Mineral Resources Data System to list known Colorado historical mines by county. Each county site has links to the known mines within its borders. Some are known and named, others are unnamed. Mines should be assumed to be on private property unless other research is conducted. Data provided for each mine site include: Name, State, County, Elevation, Primary Mineral Mined, Latitude and Longitude and a link to Google Maps. Photos are provided where available. Additional information for some Mines are satellite photos, and ownership, business and historical records. Mining History is an historical site that provides information on mining, mining towns, the gold and silver rush, and Photos and maps of the western United States. This is a great database for student historical research or data and statistics classes. Consider becoming a member or making a donation to help further the work of the site.

The Pastime Saloon: Stop 8 Museum of the West Virtual Tour. Watch this short video to learn about a Museum of the West exhibit or collection to preview your field trip or for a virtual field trip if you are unable to attend in person. The Museum of the West is part of the Museums of Westen Colorado. Saloons were gathering places during the early days of Grand Junction. Curator of History, David Bailey, describes what went on in these gathering places.

This collection uses primary sources to explore the politics of the Gilded Age. Digital Public Library of America Primary Source Sets are designed to help students develop their critical thinking skills and draw diverse material from libraries, archives, and museums across the United States. Each set includes an overview, ten to fifteen primary sources, links to related resources, and a teaching guide. These sets were created and reviewed by the teachers on the DPLA's Education Advisory Committee.

Perigo, CO Mining Town. Western Mining History presents a brief summary of Colorado's Historical Mining Towns with links to additional Colorado resources for a mining town database and mines by county. Western Mining History is an historical site that provides information on mining, mining towns, the gold and silver rush, and Photos and maps of the western United States. This is a strong primary source resource that can be used for a variety of class research projects. Consider becoming a member or making a donation to help further the work of the site.

Perseus is an evolving digital library, engineering interactions through time, space, and language. Our primary goal is to bring a wide range of source materials to as large an audience as possible. We anticipate that greater accessibility to the sources for the study of the humanities will strengthen the quality of questions, lead to new avenues of research, and connect more people through the connection of ideas.

This collection uses primary sources to explore perspectives on the French and Indian War. Digital Public Library of America Primary Source Sets are designed to help students develop their critical thinking skills and draw diverse material from libraries, archives, and museums across the United States. Each set includes an overview, ten to fifteen primary sources, links to related resources, and a teaching guide. These sets were created and reviewed by the teachers on the DPLA's Education Advisory Committee.

The photo analysis worksheet was designed and developed by the Education Staff of the National Archives and Records Administration. You may find this worksheet useful as you introduce students to photographs as primary sources of historical, cultural and social information.

The photo analysis worksheet was designed and developed by the Education Staff of the National Archives and Records Administration. You may find this worksheet useful as you introduce students to photographs as primary sources of historical, cultural and social information.

This lesson covers the process of photosynthesis and the related plant cell functions of transpiration and cellular respiration. Students will learn how engineers can use the natural process of photosynthesis as an exemplary model of a complex yet efficient process for converting solar energy to chemical energy or distributing water throughout a system.

Pitkin, CO Mining Town. Western Mining History presents a brief summary of Colorado's Historical Mining Towns with links to additional Colorado resources for a mining town database and mines by county. Western Mining History is an historical site that provides information on mining, mining towns, the gold and silver rush, and Photos and maps of the western United States. This is a strong primary source resource that can be used for a variety of class research projects. Consider becoming a member or making a donation to help further the work of the site.

This Western Mining History database uses Mineral Resources Data System to list known Colorado historical mines by county. Each county site has links to the known mines within its borders. Some are known and named, others are unnamed. Mines should be assumed to be on private property unless other research is conducted. Data provided for each mine site include: Name, State, County, Elevation, Primary Mineral Mined, Latitude and Longitude and a link to Google Maps. Photos are provided where available. Additional information for some Mines are satellite photos, and ownership, business and historical records. Mining History is an historical site that provides information on mining, mining towns, the gold and silver rush, and Photos and maps of the western United States. This is a great database for student historical research or data and statistics classes. Consider becoming a member or making a donation to help further the work of the site.

Placerville, CO Mining Town. Western Mining History presents a brief summary of Colorado's Historical Mining Towns with links to additional Colorado resources for a mining town database and mines by county. Western Mining History is an historical site that provides information on mining, mining towns, the gold and silver rush, and Photos and maps of the western United States. This is a strong primary source resource that can be used for a variety of class research projects. Consider becoming a member or making a donation to help further the work of the site.

Plankton to Plastic Pollution STEM Kit. The Natural Sciences Education & Outreach Center collaborates with CSU faculty, National Parks and citizen science programs to translate their current scientific research into unique STEM experiences for students in the form of Educational Kits that can be checked out. Each kit contains just about all of the materials needed (minus common things like water and paper towels) to explore some really interesting scientific research topics. The kits are available for teachers and informal educators in Colorado to check out for a duration of a week by submitting either a local pickup form or a delivery form available at the linked website. Please use the contact information on the STEM Kit overview page to learn more. https://www.cns-eoc.colostate.edu/stem-kits/ This kit is provided free for educational use. This resource is also available in Spanish in the linked file.

Platoro, CO Mining Town. Western Mining History presents a brief summary of Colorado's Historical Mining Towns with links to additional Colorado resources for a mining town database and mines by county. Western Mining History is an historical site that provides information on mining, mining towns, the gold and silver rush, and Photos and maps of the western United States. This is a strong primary source resource that can be used for a variety of class research projects. Consider becoming a member or making a donation to help further the work of the site.

This collection uses primary sources to explore the poetry of Emily Dickinson. Digital Public Library of America Primary Source Sets are designed to help students develop their critical thinking skills and draw diverse material from libraries, archives, and museums across the United States. Each set includes an overview, ten to fifteen primary sources, links to related resources, and a teaching guide. These sets were created and reviewed by the teachers on the DPLA's Education Advisory Committee.

This collection uses primary sources to explore the poetry of Maya Angelou. Digital Public Library of America Primary Source Sets are designed to help students develop their critical thinking skills and draw diverse material from libraries, archives, and museums across the United States. Each set includes an overview, ten to fifteen primary sources, links to related resources, and a teaching guide. These sets were created and reviewed by the teachers on the DPLA's Education Advisory Committee.